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・ Nitronate monooxygenase
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Nitric-oxide synthase (NAD(P)H-dependent)
・ Nitrica
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Nitric-oxide synthase (NAD(P)H-dependent) : ウィキペディア英語版
Nitric-oxide synthase (NAD(P)H-dependent)

Nitric-oxide synthase (NAD(P)H-dependent) (, ''nitric oxide synthetase'', ''NO synthase'') is an enzyme with system name ''L-arginine,NAD(P)H:oxygen oxidoreductase (nitric-oxide-forming)''. This enzyme catalyses the following chemical reaction
: 2 L-arginine + 3 NAD(P)H + 3 H+ + 4 O2 \rightleftharpoons 2 L-citrulline + 2 nitric oxide + 3 NAD(P)+ + 4 H2O (overall reaction)
:(1a) 2 L-arginine + 2 NAD(P)H + 2 H+ + 2 O2 \rightleftharpoons 2 Nomega-hydroxy-L-arginine + 2 NAD(P)+ + 2 H2O
:(1b) 2 Nomega-hydroxy-L-arginine + NAD(P)H + H+ + 2 O2 \rightleftharpoons 2 L-citrulline + 2 nitric oxide + NAD(P)+ + 2 H2O
Nitric-oxide synthase (NAD(P)H-dependent) binds heme (iron protoporphyrin IX) and tetrahydrobiopterin.
== See also ==

* Nitric oxide synthase

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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